HEART, VESSELS AND TRANSPLANTATION
An international peer-reviewed multidisciplinary journal on cardiovascular diseases and all relevant disciplines
experimental and clinical research articles, reviews,
case reports, brief reports, images
cardiovascular surgery, surgery and transplantation
articles on cardiovascular diseases and broader disciplines
Original research articles, review articles, and case reports
Original research articles, review articles, and case reports
On sweet undeniable feeling of power of international intellectual feudalism, bias, discrimination, censoring and theft
This is a first piece we open for debate and discussion. As every editor can comprehend from the title of this short introduction, this is about may be some journal editors have experienced or it may only be intrinsic for our journal.
This is to notify that we prolong the time for review and revision for manuscripts we receive for consideration for publication for authors, reviewers and editors involved in the fight against COVID -19.
The Heart, Vessels and Transplantation journal, Center for Scientific Research and Development of Education, Bishkek, Kyrgyzstan and British Council office invite you to take part in online Academic English Writing Course that starts on January 2023 (Every Monday and Wednesday 5-6 pm Bishkek time ).
Center for Scientific Research and Development of Education organizes course online echocardiography for beginners for physicians, residents and interns. The course starts on September 12, 2022, 2 times per week 4.30-5.30 pm Bishkek, Kyrgyzstan time, every Monday and Thursday.
Center for Scientific Research and Development of Education organizes online course on biomedical statistics that will help you understand and use statistics for your scientific work, thesis and dissertations and manuscripts. The course starts on April , 2023, 8-9.30 pm Bishkek, Kyrgyzstan time, every Tuesday and Thursday for 5 weeks.
International Research School organized by Heart, Vessrls and Transplantation journal and CSRDE will be held in November 2022 online, semi-virtual format is also on agenda if global pandemics sitiation will allow to make semi-virtual. We invite young researchers, residents, PhD students and junior faculty members of universities, research institutons, teaching hospitals who would like to acquire research skills in preparation of scientific project.
In this article we highlighted the blood pressure management in elderly patients with orthostatic hypotension.
Intra-aortic balloon pump (IABP) is widely used as a mechanical support device. Current evidence after the IABP-SHOCK II trial is ambiguous. We evaluated the impact of IABP on hemodynamic parameters (Cardiac Output (CO), Cardiac Power Output (CPO) and Systemic Vascular Resistance (SVR)) measured at 6 and 24 hours in patients presenting with cardiogenic shock (CS) with Acute Coronary Syndrome (ACS) amongst Asian Indians.
On the stage of left atrial percutaneous procedures a number of acute complications and their management have been described. In the current brief report, coronary air embolism, its acute manifestations, differential diagnosis and outcomes were presented in three patients who underwent cryoballoon ablation of atrial fibrillation and left appendage closure.
We present the case of a pregnant woman with Wolf-Parkinson-White syndrome with recurrent episodes of tachycardia, refractory to antiarrhythmic drug therapy, who underwent catheter ablation of a left lateral accessory pathway without the use of fluoroscopy.
We are committed to evaluate by means of independent peer-review your manuscripts and produce evidence-based science and medical knowledge, as well as bring to your attention comprehensive knowledge aimed at improving your clinical practice and provide continued medical education.
Sepsis is the result of the hosts’ response to an infectious agent, leading to organ dysfunction (1). It is a very common syndrome, estimated to have occurred in 48.9 million people in 2017, which represented an incidence of 677.5 (535.7–876.1) cases per 100,000 in the same year
Aorto-iliac occlusive disease (AIOD) is a common atherosclerotic disease causing significant morbidity. Transatlantic intersociety consensus for the management of peripheral arterial disease (TASC II) recommends endovascular therapy (ET) for better management of patients with lesions type A and B. With the advent of endovascular therapy, type C and D lesions management is becoming more feasible with endovascular therapy than open surgery for aorto-iliac occlusive disease. We aimed to evaluate patients with AIOD and to describe short-term outcome of endovascular treatment for such lesions.
As a result of reviewing and studying the studies, it can be concluded that the replacement of the aortic valve with minimally invasive methods is more effective.
Primary percutaneous coronary intervention (PCI) is the preferred reperfusion therapy for ST elevation myocardial infarction (STEMI) patients in the first 12 hours after symptom onset, provided it can be performed quickly (120 minutes from STEMI diagnosis) by an experienced team
During the last two years, our professional as well as personal lives have been considerably influenced by the COVID 19 pandemics. This situation has required fundamental changes how to approach and maintain our activities. However, in spite of the pandemic situation we continue organizing the International Research Interdisciplinary School (IRIS) courses annually for already 16 years.
The updated ESC guidelines for the prevention of cardiovascular diseases (CVD)
Preoperative CPET before elective CABG was feasible and safe. However, a large proportion of patients did not achieve the anaerobic threshold. Therefore, VE/VCO2 slope, OUES and HRR may be the most useful CPET variables in the preoperative period.
This study showed that normotensive non-dipper patients had inflammation as much as dipper hypertensive patients according to measurement of MPV, RDW systemic inflammation index, PLR, NLR levels.
The purpose of this article was to highlight the points to be considered in blunt traumatic aortic injury due to high-energy motor vehicle accident.
We present a case of a large patent ductus arteriosus closure with Amplatzer ductal occluder in a 14-month-old girl with low birth weight.
We demonstrated that in cases when the antergrade access to CTO is not possible, femoral vein retrograde access with transseptal puncture with coronary intervention and stenting can be used successfully.
New sections have appeared concerning patient workout before implantation, but also concerning the new modalities of conduction system pacing, and a new section on perioperative management. We summarize here the key points from these International guidelines.
Heart failure (HF) is a major health problem affecting millions of people worldwide. The report about heart disease and stroke statistics claimed that almost 6.0 million Americans ≥20 years of age had HF based on the results of 2015-2018 The National Health and Nutrition Examination Survey (NHANES) (1)
The current guidelines are a breakthrough in the approach to heart failure not only because of new therapies, but mainly because of the approach to treatment. The newest recommendations mark the beginning of an era in which personalization of implemented therapies comes to the fore
The cTnT/CK-MB ratio was superior to its components in predicting changes in LV function after STEMI. The cTnT/CK-MB ratio can be used in clinical practice for risk stratification and treatment optimization.
Percutaneous coronary diagnostic and therapeutic procedures are very frequent worldwide and therefore bring to discussion the best vascular access for each patient. The vascular access for coronary angiography or coronary interventions must be chosen according to the patient's clinical and anatomical characteristics, as well as the experience of the interventional cardiologist. Several studies have shown the superiority of radial access compared to femoral access, reducing local complications, major cardiovascular events, death and hospital costs. The ulnar approach is a feasible and safe option in the absence of radial access.
Bradycardia during the early period following heart transplantation frequently occurs with an incidence of 14 to 44% and it is usually self-limited. The incidence of late bradycardia (from 30 days to more than 5 or 6 months after transplantation) has been reported to be 1.5%. A 33-year-old male patient with a history of orthotopic heart transplantation in 2013 presented with complaints of dizziness and near syncope. A DDDR permanent pacemaker was implanted for sinus pauses exceeding 3 seconds recorded on Holter examination. Shortly after the procedure, he developed sudden cardiovascular collapse. Cardiopulmonary resuscitation was performed and a pulse steroid treatment (2 grams of methylprednisolone) was given. After 2 days, the patient was extubated. While making preparations for re-transplantation, cardiopulmonary arrest developed again and he died. Sinus pause may be a clue for rejection and is an important finding in predicting clinical course.
We report a case of a 55-year-old gentleman who had undergone thoracic EVAR. Thirty months after the given procedure he presented with RTAD and underwent supracoronary aortic replacement. The article is intended to remind the clinicians of the importance of early detection of the possible complications when performing EVAR, and the significance of a rapid response.
We present a case of a 78-year-old female patient who was admitted to our hospital with progressive dyspnea and chest pain. Echocardiography revealed multiple masses of different shape and size in the left atrium, the left and right ventricles. Cardiac magnetic resonance confirmed multiple cardiac masses with signs of invasion in the myocardium and heterogeneous late gadolinium enhancement in all these masses. A biopsy of the abdominal mass revealed an undifferentiated pleomorphic sarcoma.
Nina Starr Braunwald - first female heart surgeon, a pioneer in cardio-thoracic surgery, certified by the American Board of Thoracic Surgery and the first elected to the American Thoracic Surgery Association, a wonderful wife and mother of three daughters, teacher and mentor of several generations of doctors. We will tell everyone about this in more detail in our historical note
For a long time, medicine was the prerogative of men, and women were not allowed to this area. And despite the prohibitions and moral values of those times, women left a mark in the history of medicine.
His-bundle pacing (HBP) appears to be a viable stand-alone or adjunctive physiological pacing therapy in pacemaker dependent patients. It could also serve as an effective adjunct or alternative pacing therapy for heart failure patients who require cardiac resynchronization therapy or pacemaker upgrade. His-bundle pacing has demonstrated improvement of His-Purkinje conduction, left ventricular electrical / mechanical synchronization, and left ventricular ejection fraction (LVEF) compared with right ventricle pacing.
In this review article we summarized the differential diagnosis of radiological signs of pneumonia associated with COVID-19 infection and emphasized learning points.
The case of a patient with repetitive syncope episodes with a history of using loperamide at high doses for recreational purposes in search of an effect similar to heroin, is reported. In the diagnostic approach with Holter monitoring, ventricular tachycardia and ventricular fibrillation were evidenced. We also present the treatment of our case and review the literature.
This article discusses the easy way and steps to interpret an electrocardiogram (ECG). ECG is one of the hardest topics for medical students, young medical doctors, cardiac nurses and other health professionals, that is why this topic has been chosen in order to help them to understand how to interpret ECG easily.
We would like to open a discussion on this topic - how to teach young researcher the soft skills required for doing research, as well as how to combine the on-line and in-person formats in an optimal way.
The 4th Annual Scientific-Practical Conference on Mini-invasive and Innovative Cardiac Surgery devoted to the memory of Isa K. Akhunbaev was held between 19-22 June 2021, in Bishkek and Baet, Issyk-Kul, Kyrgyzstan.
In this issue March 2021 issue of the Heart, Vessels and Transplantation journal you may find editorial on what is new in 2020 atrial fibrillation (AF) guideline, research article on pericardial involvement after cardiac surgery and reviews on syncope evaluation and biomarkers in congenital heart disease, case reports on infectious endocarditis in acute coronary syndrome, Texidor`s twinge as a cause of chest pain, quizzes on electrocardiography and interventional cardiology, and interesting commentary on literature and medicine.
The main purpose of this review is to highlight the indications for HUTT and indicate situations in which it should be avoided due to the lack of added value of the applied therapy.
In this review, we aimed to analyze recent studies concerning the role of the NT-pro-BNP in pediatric cardiac patients with pulmonary hypertension.
Presentation of an acute coronary syndrome related to infective endocarditis is rare but potentially lethal. For young people, acute myocardial infarction and an infection syndrome should lead us to suspect IE.
Various maneuvers like lying down or sitting upright and attempting deep inspiration tends to help in such conditions. This case report is reporting an unusual presentation of this syndrome due to its long duration of episode than the duration described in the previous reports.
A-60-year-old male, attended to cardiology outpatient clinic with a numbness for 1 week without chest pain. In his medical history, no hypertension or diabetes mellitus was present.
The following piece is a reflection concerning the interplay between the art of writing and the art of medicine. We are exploring the similarities and disparities of the field with a focus on doctors – medical students and fiction authors/poets.
An analysis of the current situation in the Kyrgyz Republic demonstrates that the areas of concern in care system for patients with cardiovascular diseases (CVD) are the insufficient and untimely identification of cardiovascular risk factors, as well as their ineffective management due to the incomplete implementation of existing risk stratification guidelines and decision-making. This study assesses distribution of total cardiovascular risk among the population of the Kyrgyz Republic using the WHO/ISH risk scale. In addition, the distribution of the main risk factors separately is calculated, as well as the frequency of some additional CVD risk factors that are not included into the WHO/ISH evaluation scale is estimated.
Our observational study demonstrated significant improvement in oxygen saturation, reduction in inflammatory markers – leukocytosis, CRP and D-dimers and 83% recovery without need for mechanical ventilation and no mortality in patients with COVID-19 with severe multilobar bilateral pneumonia and CT score 3-4 receiving tocilizumab in addition to standard treatment.
New techniques and special bifurcation stents may possibly overcome some limitations of the using two stents and revolutionize the management of PCI of bifurcation lesions of the coronary arteries in the future.
A 68-year-old patient with history of recent coronary artery bypass surgery (CABG) was admitted to our hospital with incessant monomorphic ventricular tachycardia (VT) and was treated successfully with radiofrequency catheter ablation (RFA).
Cystic adventitial disease (CAD) is a very rare vascular disorder with prevalence as low as 1:1000 of all vascular pathologies (1). This disease most frequently occurs in young or middle-aged male patients with male/female ratio of 5/1
A 55 years old male patient with severe coronary artery disease was sent to our echocardiography lab for preoperative evaluation.
A 25-year-old male, without cardiovascular risk factors or cardiovascular history, was referred to our hospital for recurrent angina. Thirty days before he presented the signs of a clinical myocardial infarction without receiving medical assistance.
The IRIS Kyrgyzstan 2020 represents further important step in moving IRIS into the virtual space (1, 2). The first full on-line course Kyrgyzstan 2020 digital was held on October 23-27, 2020, organized by the Center for Scientific Research and Development of Education, SRI of Heart Surgery and Organ Transplantation, National Center of Cardiology and Internal Medicine, and International School of Medicine, Bishkek, Kyrgyzstan, under the under patronage of Heart Vessels and Transplantation journal, under the leadership of Gulmira Kudaiberdieva.
T wave peak-to-end interval is a measure of transmural dispersion of repolarization and accepted as a surrogate for increased ventricular arrhythmogenesis risk. Our findings show that ASD patients whose shunt ratio are ≥2.0 show increased risk for arrhythmias.
We aimed to define the relationship of preoperative N-terminal-pro-brain type natriuretic peptide (NT-pro-BNP) testing in routine practice of cardiac surgery with clinical, perioperative variables, surgical outcomes and complications in pediatric and adult cardiac surgery patients. In addition, we assessed relationship of NT-pro-BNP with EuroSCORE II in adult patients undergoing cardiac surgery.
The use of the laboratory criterion NT-proBNP makes it possible to objectively diagnose myocardial dysfunction with high analytical sensitivity and specificity; nevertheless, it is always necessary to compare complaints and Echo-CG data with NT-proBNP data.
Worldwide spread of coronavirus disease (COVID-19) caused overwhelming mortality rate during preceding half of the year 2020. Although coronavirus infection was known for mostly respiratory tract involvement, novel COVID-19 pandemic showed excessive cardiac mortality and arrhythmic complications. We aimed to summarize current literature and emphasize on underlying pathological mechanisms and global point of view to coronavirus and arrhythmia relationship.
We present here the case of acute coronary syndrome (ST elevation myocardial infarction) with total occlusion of right coronary artery successfully treated with PCI and stenting during COVID-19 pandemics.
International Research Interdisciplinary School 2020 in Slovakia will be held on September 12-15, 2020.
International Research Interdisciplinary School 2020 will be held in virtual online format (due to pandemics restrictions) on October 23-27, 2020.
We would like to welcome our new editors: on cardiovascular diseases, pulmonary disease and pulmonary hypertension – Dr Baktybek Kojonazarov from Gessen, Germany; on cardiovascular surgery - Dr Jeffrey Shuhaiber from Boston MA, USA; on cardiology and high-altitude medicine - Prof. Akpay Sarybaev, Bishkek, Kyrgyzstan and on nuclear cardiology and cardiology - Dr Andrea Rocha de Lorenzo from Rio de Janeiro, Brazil. Our team of editors’ feels enriched with invaluable expertise of our new members.
The maximum number of cases of coronavirus infection was 79 (tested positive cases, including asymptomatic and cases with clinical manifestations) as of April 12, 2020. According to the forecast by the WHO methodology, the peak incidence of COVID-19 should be at the eighth week of the development of the epidemic process, amounting to 92 cases. Starting from the fifth week, the number of cases of COVID-19 tends to decrease gradually and the mathematical model for predicting the incidence of COVID-19 in the Kyrgyz Republic shows that by the end of May 2020, 97% of the total number of infected with coronavirus will be detected.
The understanding of the pathophysiology of cardiovascular complications in COVID-19 is a key to the implementation of therapeutic measures, which may offer additional benefits, mainly for patients with severe disease, such as anticoagulants.
This study shows the possibility of implanting the right size of the artificial heart valve, with rheumatic lesions of the mitral valve with the complete preservation of subvalvular structures.
The aim of this investigation is to study clinical, laboratory, neurosonography and electroencephalography characteristics of preterm infants with VLBW and ELBW with hypoxic of CNS on complex comprehensive nutritional support, diagnostic criteria of which were infants body weight gain, increase in growth and head circumference
In this review, we aimed to represent recent physiological and clinical standpoints regarding to athletic heart syndrome as well as its difference from sedentary heart changes and pathological hypertrophy, its association with sudden cardiac death.
Thus, our case demonstrated reduction of left atrium early in postoperative period and its slow reduction after surgery during 1 year. It is also showed human reserve capacity and possibility of left atrial dilatation to such sizes. Late diagnosis of such changes in heart is possibly related to the fact that patient was afraid to see doctors and undergo surgery. The left atrial cavity size determination can be done intraoperatively using method of surgical glove we suggested.
This case highlights it is necessary to investigate balance between efficacy and safety of lopinavir/ritonavir for COVID-19 therapy. Off –label prescribing lopinavir/ritonavir outside of a clinical trial setting should be avoided until the data have proven that treatment benefit over placebo.
The prognosis of the indigenous people of the high-altitudes of Kyrgyzstan regarding the risk of developing T2DM depends on phenotypic factors and living conditions in the high altitudes, with hypoxia playing the leading role. Among the highlanders of Kyrgyzstan, metabolic factors are dominated by abdominal obesity, and it is likely that regular intake of fruits and vegetables is effective to reduce the risks of developing diabetes, along with the fight against other negative factors.
Occurrence of complications and conversion to conventional surgical cholecystectomy reduced over time, depending on surgical experience of operating team and practice of operator.
This review is devoted to comprehensive echocardiographic analysis of right ventricular function - right ventricular strain rate analysis.
The following 12-lead electrocardiogram (ECG) tracing is provided from a 72 years old male patient implanted with a dual-chamber pacemaker (Medtronic Astra DR), when applying a magnet. He underwent three previous persistent atrial fibrillation and atrial tachycardia radiofrequency ablations, and an additional atrioventricular node ablation procedure (left ventricular ejection fraction 45%). The patient does not report any cardiovascular symptom.
International Research Interdisciplinary School 2020 will be held on June 7-12 at the shore of the pearl of Kyrgyzstan – Bayet, Issyk-Kul lake.
International Research Interdisciplinary School 2020 in Slovakia will be held on September 12-15, 2020.
To define epidemiological and nosological structure of patients with chronic heart failure (CHF) according to hospitals of tertiary level of the Kyrgyz Republic (National Center of Cardiology and Therapy and Scientific Research Institute of Heart Surgery and Organs Transplantation).
Left ventricular ejection fraction (LVEF) is the most frequently used echocardiographic parameter. LVEF based heart failure classification, timely intervention in a patient with valvular disease (e.g. aortic stenosis, mitral regurgitation), deterioration of myocardial function in a patient treated with chemotherapy; all need a simple LVEF value for decision-making process.
A 39-year-old female patient who had aortic and mitral valve replacement due to rheumatic heart disease was also found to have cystic mass in the right ventricle on echocardiography during late routine control. The cystic mass identified on echocardiography was shown to be a pseudoaneurysm that develops from the membranous section of the interventricular septum and grows toward the right heart by ECG-triggered cardiac computed tomography performed for differential diagnosis. Because the patient did not accept the surgery, regular follow-ups were recommended.
According to results of our study, combined surgical interventions especially those performed from a single surgical approach, slightly increase the severity of the operation compared to isolated interventions performed for the same underlying diseases. Evidence reveals that simultaneous operations are not followed by severe operational complications, which could be an expected feature of solely this type of operation.
On October 25-26, 2019 the annual international scientific-practical conference "School of Arrhythmology" was organized by the main cardiac surgical medical institution of Kyrgyzstan - "Scientific Research Institute of Heart Surgery and Organ Transplantation" under the Ministry of Health of Kyrgyz Republic.
In this review, the recent developments about the accesses for pacemakers and ICD will be described: the axillary and the femoral vein. The His bundle pacing and the advantages of the entirely subcutaneous defibrillator will also be presented.
Foods have a wider role besides simply satisfying hunger, and the gut may be the source of several diseases. The human gut is populated by 100 trillion microorganisms and the most abundant phyla are the Firmicutes ( 60 a 80%), such as the lactobacilli, and the Bacteroidetes ( 20 a 40%), such as the gender Bacteroides.The obesity epidemics may be related to the constant availability of food, less physical exercise, and influences on the gut microbiota such as type of food ingested (low fiber, high calorie, and high fat).
A 66 years old woman with known dilated cardiomyopathy and severely reduced ejection fraction presented with bundle branch reentrant tachycardia. Bundle branch reentrant tachycardia is an uncommon form of ventricular tachycardia incorporating both bundle branches into the reentry circuit. The diagnosis is based on electrophysiological findings and pacing maneuvres that prove participation of the His- Purkinje system in the tachycardia mechanism.
We describe a case of Streptococcus alactolyticus infective endocarditis complicated by bacteriemia. A 64-year-old male with a previous history of coronary artery bypass grafting applied to our cardiology outpatient clinic with complaints of dyspnea, fever, confusion and an apical holosystolic murmur.
In the year 2019, two IRIS courses were held, one in Ukraine and one in Slovakia, completing the total number of 25 courses since the year 2006.
Between 14-18 May 2019 in Bishkek, Kyrgyz Republic at SRI of Heart Surgery and Organs Transplantation of Ministry of Health of Kyrgyz Republic master- classes on transcatheter aortic valve replacement, combined valvular heart diseases surgery and coronary bypass surgery, congenital heart diseases surgery: mini-invasive surgery of complex congenital heart diseases and thoracoscopic correction of congenital heart diseases, combined surgery of aortic root and coronary artery diseases, on interventional arrhythmology and cardiology, interventional closure of congenital heart diseases, on intraoperative transesophageal echocardiography took place.
In this June 2019 issue of the journal you can find article on management of deep venous thrombosis in general surgery, review article on strategy of preservation subvalvular structures in mitral valve replacement surgery and quizzes on electrophysiology and pacemaker.
Venous thromboembolism (VTE) in the form of either pulmonary embolism (PE) or deep vein thrombosis (DVT) complicates major surgery not infrequently. We analyzed in this study superiority of combined approach of thromboprophylaxis compared to conventional nonpharmacological preventive sets.
Complete preservation of leaflets for mitral valve replacement to maintain geometry and the function of left ventricle in the near and distant period is necessary. The aim of study was to analyze these procedures. Bileaflet preservation of the anatomical architectonics of the left ventricle in combination with the surgical reduction of the enlarged left atrium will allow to optimize the postoperative geometry and to improve the remodeling of all the left heart along with improved long-term results of patients with mitral valve replacement.
A routine follow-up twelve-lead ECG (Fig. 1) is performed in a 70 years old male patient implanted with a dual-chamber pacemaker for sick sinus syndrome two years ago (Model Reply DR, Sorin)
"Innovations in cardiac surgery: from finger mitral commissurotomy to heart assist devices." 15-19 may 2019
The IRIS program provides an environment for developing skills to carry out research projects, based on a practical, problem-based approach; and to establish enjoyable cross discipline/cross cultural collaboration.
In diabetes mellitus (DM) type 2, there is a very high risk of developing cardiovascular (CV) events. We aimed to study the total CV risk of the indigenous people of Kyrgyzstan with impaired carbohydrate metabolism (DM type 2 and impaired glucose tolerance, IGT), depending on the region of residence (low and high altitudes), and to develop targeted preventive measures.
As the gathered statistic data shows, the growing surgical experience leads to the decrease of the conversion rate, complications, hospital stay and mean operation time.
We present review of current evidence on ischemic heart disease in women. The risk factors, clinical manifestations, diagnosis and treatment and prevention of ischemic heart diseases in women are discussed.
In this article, we provided summary of knowledge on left ventricular posterior wall rupture as a complication of mitral valve replacement surgery and shared our experience with such complication.
A 27-year-old patient with episodes of syncope and short episodes of documented tachycardia. What is the possible cause of syncope?
Which location is the pulse wave flow belongs to? What kind of abnormality you can see in this flow sample?
Woman, 46 years, complains of episodes of weakness, feeling of heat in the face, palpitations and tachycardia. Sometimes these symptoms make her wake up at night.
Erasmus+ is a program of the European Union in the field of education, the main purpose of which is to improve the quality of education and the development of mobility. At the same time, cultural exchange takes place among all participants between students and teachers and friendly relations arise. The program also creates the basis for international cooperation for university teachers in various countries.
We read with great interest the case report of Tuleutayev and co-authors (1) published in Heart, Vessels and Transplantation. In this case report, authors present a 61-year-old male patient admitted to the emergency department with chest pain. Multidetector computed tomography (MDCT) revealed aortic root aneurysm and right coronary artery (RCA) origin anomaly with related myocardial infarction. Images of a very good quality and satisfying information before and after surgical treatment were presented.
In this last issue of the year 2018, we published original research article on role of cytokines in hypertension with LVH and surgical AF ablation, interesting case report and challenging quiz on paced ECG, as well as invited review on advances on echocardiography.
Our study demonstrates the modulating role of inflammation on the processes of myocardial remodeling in hypertension.
Objective: To evaluate the presence of sinus rhythm or atrial fibrillation (AF) in patients who had mitral valve surgery with concomitant surgical ablation of AF, by unipolar or bipolar radiofrequency.
Echocardiography has the long development history beginning with amplitude imaging. Nowadays, two- and three- dimensional imaging are standard tools available in almost every echocardiography machine. Myocardial deformation imaging is gaining popularity out of research projects. The future will bring new and sophisticated tools for echocardiographic analysis such intracardiac flow imaging and an automated 3D volume calculation.
The aim of our case report is to describe rare anomaly of coronary artery origin concomitant with aortic root aneurysm, as well as to present the results of surgical correction of this pathology.
Usenbek B. Baisakov physician by vocation, who devoted himself to serve medicine, was a careful attentive family man, a husband and a father, a kind colleague.
In this issue, we published the editorial about prominent surgeon, founder of cardiovascular surgery in Central Asia who performed first heart surgery – Professor Isa K. Akhunbaev.
“With my work, I am the son of my nation. Before these people I bow. People, I'm your slave. Not only with work, but with my blood I belong to you. I am Isa.” It is dedicated to the 110th anniversary of Academician Isa Akhunbaev
To study the nature of changes and peculiarities of the menstrual function in adolescent girls, internal migrants from the highland regions of the republic, depending on the length of stay in lowland areas.
The present report describes one strategy used for cardiopulmonary rehabilitation and to help wean a patient from mechanical ventilation, with prohibitive comorbidities that contra-indicate surgical mitral valve repair, using respiratory and peripheral muscle training associated with positive pressure ventilation
Beautiful nature, Issyk-Kul, common interests, close cultures (8 participants from Kyrgyzstan and 1 from Kazakhstan), informal and high professional skills of the faculty created a very friendly environment. Participants do not forget the evening at the Faculty home. The participants were interested in the scientific career of Gulmira and Jonathan, their completed and planned scientific projects, the history of the IRIS school, told about their successes, problems and plans for the future.
For the first time in Kyrgyz Republic, the first scientific and international Arrhythmology School was organized by main cardiac surgery of Kyrgyzstan – Scientific Research Institute of Organ Transplantation (SRIHSOT) with support of Ministry of Health. The conference Contemporary Methods of Arrhythmia Diagnosis and Treatment of Arrhythmias for Cardiologists and Family Physicians took place on 19.06.2018 in cultural center Asanbai.
The Note on page 36, right upper corner line 1: Heart Vessels and Transplantation 2018; 2: 35 must read Heart Vessels and Transplantation 2018; 2: 36-37. Editorial office apologizes for the typo print error.
We also announce the educational activity our journal is involved- International Research Interdisciplinary School (program developed at Duke University, Durham, NC, USA) that will be held on the shore of Issik-Kul, Kyrgyzstan in June 2018, this is the second school in our country, which was held in many countries all over the globe ..
Infective endocarditis (IE) is a severe condition with high morbidity and a high in-hospital and 5- year mortality . Part of the strategy to decrease mortality is early diagnosis, adequate antimicrobial treatment and best surgical timing as well as access to surgery. Establishing the causative pathogen is of paramount importance, and in most settings routine blood cultures are used for this purpose, although other sites may be cultured, such as distant emboli. Besides this, serological diagnosis may important in suggestive epidemiological scenarios, especially for Bartonella spp and Coxiella burnetii.
The following protocol is intended to be a useful and practical guide to empirical and pathogen directed antimicrobial therapy of infective endocarditis (IE) in adult patients
Recently, the Higher Attestation Commission (HAC) of the Kyrgyz Republic has been actively working to improve the quality of scientific research on the basis of which theses are defended and scientific personnel are certified. Previously the basic requirement for the publication of scientific research results concerned mainly the number of published works.
Candidemia was an uncommon infectious complication, but associated with a significant mortality. Our data support the identification of high-risk cardiac surgery patients who may benefit from empirical antifungal therapy.
In this study, we sought to study the structure of newly diagnosed CHD and the age of the diagnosis within Kyrgyz Republic.
This article provide an overview of studies on indications, surgery and outcomes of valvular heart disease surgery in elderly patients.
International Research Interdisciplinary School at the shore of the pearl of Kyrgyzstan – Issyk-Kul lake. The 5-day workshop program created at the Duke University, Durham, USA, is the training program on how to prepare a scientific project and how to work in multidisciplinary international team. The language of school is English.
Another question I hear frequently from students, junior researchers and clinicians, is related to the selection of the research field for their future research career: “What field of science is THE FIELD for an exciting research, for being a successful and recognized researcher and for contributing to innovations?” And a related question: “Is it possible to do research without new sophisticated equipment?”, or in other words: “Is it possible to do a good research when I do not have latest (expensive) technology or I am not in the new emerging promising field of science”?
Thus our study demonstrated accesibility of surgical care for elderly patients is the highest for the urban areas with specialized cardiac surgery centers, where patients referred from rural regions.
Patients with replaced heart valve submitted to echocardiographic examination may have symptoms related either to valvular malfunction or ventricular dysfunction from different causes. Clinical examination is not reliable in a prosthetic valve evaluation and the main information regarding its function could be obtained using different cardiac ultrasound modalities. This review provides a description of echocardiographic and Doppler techniques useful in evaluation of prosthetic heart valves.
In this paper, we present the literature review on nutrition disorders in schoolchildren. as well as the data about the role of rational and balanced nutrition in strengthening of child and adolescent health. We provided the review of literature on the approaches in education facilities on healthy diet education and school meals.
Counterpulsation is an intervention used to restore the Windkessel effect of the aorta in the setting of hemodynamic compromise by increasing aortic pressure during early diastole that augments coronary and distal end organ perfusion as well as decreasing aortic pressure during early systole thus reducing ventricular afterload and workload
The constituent assembly of the Eurasian Association Cardiothoracic Surgeons - EAACTS was held on 19th January 2018 at Golden Tulip hotel in Bishkek, Kyrgyzstan.
Correction note: this to notify correction for manuscript: Tuleutayeva R, Mukhamedova A, Musina A, Sultanova Z, Makhatova A, Vancova M, et al. International Research Interdisciplinary School : 23-28 September 2017, Semey, East Kazakhstan region, Kazakhstan. Heart Vessels and Transplantation 2017; 1: 99-103 - page 100, legend for Figure 4. should read Team the Girls: Dinara Alibekova, Erkezhan Kalshabai Gulnara Nurgalieva: Performing - final presentation of project instead of Team the Girls: Roza Taimanova ...
To answer the question, why do we need a new medical journal in Central Asia, it is essential to understand that with transition to the new standards of scientific research in majority of Central Asian countries, the crucial need in change of approaches in biomedical publishing corresponding to worldwide standards has emerged.
Atrial fibrillation (AF) is the most common sustained arrhythmia. In the last 20 years, it has become one of the most important public health problems and a significant cause of increasing healthcare expenditures. The prevalence of AF is also increasing due to the improved ability to suspect and diagnose AF in the setting of variety of chronic cardiac and non-cardiac diseases.
The advent of advanced hematological and oncological treatment modalities including radiation therapy (RT) has led to increased survival in patients with a range of malignancies. However, this increased curative and disease free survival rate has been offset by the development of late treatment related complications, such as secondary malignancies and cardiovascular disease. This would explain why childhood cancer survivors exhibit a long-term survival rate that is significantly lower than age and gender matched population controls. When compared to the general population, the lifespan of these patients may be reduced by up to 10 years
A 14-year-old boy with Wolff-Parkinson-White syndrome underwent an electrophysiology study by the use of Navigation System Velocity Navix (St. Jude, USA) for symptoms of palpitations and persistence of pre-excitation during common exercise
Female, 77 years, complains on episodes of lightheadedness and palpitations. Fragment of ECG was recorded in night-time using 12 leads Holter monitor. Speed of the recording – 25 mm/s.
In the city of Zhovkva, near Lviv, on May 8-13, 2017, the 20th anniversary International Research Interdisciplinary School (IRIS) for young scientists working in the field of biomedical sciences was held for the first time in Ukraine. The program of this school is based on the Research Workshop developed at Duke University, USA. The initiative for the IRIS was started by the American Journal of Electrocardiology in 2006 and supported by a number of European national and international journals. The main purpose of the school was to develop the ability of its participants to plan and conduct scientific projects in biomedical disciplines.
From 2006 to now, International Research Interdisciplinary Schools (IRIS) previously called as The International Scientific Schools has provided necessary skills for its participants about research principles and research training, which have been usually forgotten in the curricula of continued medical education (1).
This year the International Research Interdisciplinary Schools (IRIS) were held in three locations in Slovakia and Kazahkstan. The purpose and methodology of the IRIS has been described in detail in previous reports (1-12). Participants in IRIS may increase the number of publications after compared to prior their participation
This is an unannounced editorial; despite we promised to give platform for our international editors I decided to write myself to answer the rhetoric question addressed by junior researchers and clinicians – does your journal has impact factor, to submit or not submit?
Our results of surgical treatment of multi-valve heart defects with infective endocarditis showed the efficacy of developed complex preoperative and intraoperative measures in surgical treatment of IE. This new treatment approach is associated with significant improvement of left ventricular function and low mortality rate.
The purpose of this study was to clarify reference values for ovarian veins diameters in women without evidence of primary or secondary pelvic venous insufficiency and to determine factors influencing these parameters.
In this review, we summarized current evidence on clinical significance, outcomes and management of postpericardiotomy syndrome and its complications developing after cardiac operations.
Prosthetic valve obstruction has an incidence ranging from 0.4% to 6% per year (1). Apart from thrombus formation, prosthetic valve obstruction can also be caused by pannus formation with variable frequency (2, 3). Correct diagnosis is of paramount importance in any patient with prosthetic valve obstruction. Real time three-dimensional echocardiography (RT 3D TEE) has the capacity to provide more in-depth analysis of any pannus related mechanical valve obstruction.
We present two rare cases of very late stent thrombosis occurring beyond ten years post initial drug eluting stent deployment.
We aimed to retrospectively analyze morbidity and mortality in recipients of kidney and liver transplant receiving immunosuppressive therapy (tacrolimus and cyclosporine with mycophenolate mofetil and mycophenolic acid). Overall, 228 patients who underwent kidney and liver transplantation were included in the study.
These are general guidelines for using statistics in medical papers in accurate and precise way (1-3). Hereafter you can find the brief excerpt of main rules for reporting statistical data (1-7). The main rule is clearly defining the research question/hypothesis and design of the study, which should guide you in selection of appropriate tests.
Galen combined passion and intensity with unusual modesty about his own accomplishments, giving credit to others’ achievements. He was a world-known scientist in electrocardiology and cardiology who trained directly and indirectly thousands of physicians around the world. Galen’s legacy is amazing and expressed in so many ways by his textbooks, excellent research, leadership at the Journal of Electrocardiology, by his inspiration for so many clinicians and researchers. We promise to continue in the IRIS mission and develop further these international courses, to utilize this unique program
Professor Ahmet Birand born in 1938, graduated from high school in Ankara. From 1955 till 1961 he underwent undergraduate studies at Medical Faculties of Ankara University and Izmir University. In Izmir, he further finished his specialization in internal medicine and in 1970, he obtained the degree of associate professor. Professor Birand had started his career at Cukurova University in Adana, in 1974 as an associate professor of internal medicine clinic.
Introducing the first issue of a new peer-reviewed international journal on cardiovascular surgery and transplantation, cardiology and broad spectrum of relevant disciplines – Heart Vessels and Transplantation, I would like to highlight main editorial and publishing policies.You may find in the next Editorial the reasons why we decided to publish a new international peer-reviewed journal
Why to publish the new journal in English language on cardiovascular medicine in the international environment of abundance in specialized journals worldwide? It is reasonable to provide the rationale for this:
Our study demonstrated that correction of tricuspid valve disease in our cohort of patients, including valve repair and replacement and reconstructive surgery of fibrous ring alone or in combination with mitral or aortic valve replacement/ repair is accompanied by reduction of tricuspid regurgitation and reduction of cardiac chamber size and right ventricular pressure. No complications intrinsic to operative technique of tricuspid valve reconstructive surgery as advanced atrioventricular block or myocardial ischemia and infarction were recorded.
In this study, we analyzed the nutrition status and morbidity of adolescents.
Left and right atria have gained interest from scientific community. Two or three- dimensional echocardiographic methods have been implemented for better understanding of atrial functions in both healthy persons and patients with various diseases. Atrial volume could be calculated from 2D or 3D images. Volumetric data and derived parameters could be used for determining atrial phasic functions.
Atrial flutter (AFL) is one of the most common supraventricular arrhythmias with macro-reentrant mechanism of atrial activation around an anatomical barrier with regular atrial rate ≥ 240 beats/min (1, 2). Despite of recent advances in invasive electrophysiology, electrocardiography (ECG) remains one of the most effective methods used for rhythm disorders diagnostics.
Echinococcosis is helminthiasis of cestodosis group characterized by formation of parasitic cysts in liver, lungs or other organs and tissues. Heart echinococcosis occurs in 0.5-2.0% of patients with generalized form of the disease. The embryos of echinococcus (scolexes) may penetrate into the heart in two ways - from the venous blood through the endocardium of the right heart and the breakout of hydatid cysts in the lung and pulmonary veins. In myocardium, scolex develops into mature hydatid cyst.
This report describes a 32 years old patient with Marfan syndrome and hypertension.
In this article, we present preliminary results of screening for congenital heart diseases (CHD) in Kyrgyz Republic. Pilot project for early diagnostics of CHD, launched in this year, shows initial results of screening in remote areas of our country.
"Continuing medical education“, "lifelong learning“, "continuous professional development“, "physicians as scholars“ – several terms with ovelapping meaning and with a commom aim. They stress the ethical obligation of healthcare professional to ensure the high quality of health care and its continuous improvement, by continuous learning , by keeping healthcare professional at the latest level of knowledge in the field (1, 2) (). Lifelong learning and continuous medical education has become the natural part of medicine.
This is a first piece we open for debate and discussion. As every editor can comprehend from the title of this short introduction, this is about may be some journal editors have experienced or it may only be intrinsic for our journal.